Hiroshi Miyazaki Selected Research

polyethylene glycol-recombinant human megakaryocyte growth and development factor (PEG-MGDF)

8/2005	Determination of thrombopoietin-derived peptides recognized by both cellular and humoral immunities in healthy donors and patients with thrombocytopenia.
9/2004	Pegylated recombinant human megakaryocyte growth and development factor suppresses the development of megakaryoblastic leukemia in mice.
10/2002	Marked improvement of thrombocytopenia in a murine model of idiopathic thrombocytopenic purpura by pegylated recombinant human megakaryocyte growth and development factor.

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Hiroshi Miyazaki Research Topics

Disease

13	Neoplasms (Cancer) 12/2019 - 01/2003
6	Thrombocytopenia (Thrombopenia) 04/2009 - 08/2002
5	Carcinogenesis 05/2013 - 03/2007
5	Neoplasm Metastasis (Metastasis) 02/2012 - 12/2007
4	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2009
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2010 - 08/2005
4	Thrombocytosis (Thrombocythemia) 06/2004 - 03/2002
3	Non-alcoholic Fatty Liver Disease 05/2014 - 01/2009
3	Squamous Cell Carcinoma of Head and Neck 04/2010 - 03/2006
3	Head and Neck Neoplasms (Head and Neck Cancer) 04/2010 - 03/2007
3	Hypertrophy 12/2006 - 08/2003
3	Lymphatic Metastasis 04/2006 - 08/2005
2	Secondary Hyperparathyroidism 01/2018 - 01/2018
2	Vomiting 01/2018 - 01/2018
2	Leukemia 11/2016 - 09/2004
2	Ischemia 01/2014 - 01/2003
2	Insulin Resistance 01/2014 - 01/2008
2	Atherosclerosis 09/2013 - 10/2000
2	Type 2 Diabetes Mellitus (MODY) 01/2013 - 01/2008
2	Infections 02/2010 - 03/2002
2	Chronic Kidney Failure (Chronic Renal Failure) 12/2006 - 10/2000
2	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 10/2002 - 08/2002
1	Dysmenorrhea (Menstrual Pain) 01/2021
1	Communicable Diseases (Infectious Diseases) 12/2019
1	Cholestasis 10/2018
1	Hyperphosphatemia 01/2018
1	Chronic Renal Insufficiency 01/2018
1	Hyperparathyroidism 01/2018
1	Hypercalcemia (Milk Alkali Syndrome) 01/2018
1	Nausea 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2014
1	Infarction (Infarctions) 01/2014
1	Cerebral Infarction 01/2014
1	Hyperglycemia 01/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2014
1	Hemorrhage 01/2014

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2014 - 04/2005
10	Thrombopoietin (c-mpl Ligand)IBA 02/2008 - 03/2002
6	EnzymesIBA 01/2014 - 03/2002
5	ChemokinesIBA 05/2013 - 04/2006
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2013 - 08/2005
4	Vitamin A (Retinol)FDA LinkGeneric 10/2018 - 01/2008
4	Vitamin E FDA LinkGeneric 05/2014 - 01/2009
4	Biological ProductsIBA 05/2013 - 08/2005
4	CytokinesIBA 05/2013 - 05/2003
4	AntibodiesIBA 10/2010 - 08/2002
4	Epidermal Growth Factor (EGF)IBA 01/2009 - 08/2005
4	Transforming Growth Factor beta (TGF-beta)IBA 09/2008 - 10/2000
3	AntioxidantsIBA 05/2014 - 01/2009
3	Methionine (L-Methionine)FDA Link 05/2014 - 01/2009
3	polyethylene glycol-recombinant human megakaryocyte growth and development factor (PEG-MGDF)IBA 08/2005 - 10/2002
3	Thrombopoietin ReceptorsIBA 09/2004 - 06/2002
2	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 02/2010
2	Cinacalcet (Sensipar)FDA Link 01/2018 - 01/2018
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018 - 01/2016
2	evocalcetIBA 01/2018 - 01/2018
2	Choline (Choline Chloride)IBA 05/2014 - 01/2014
2	Insulin (Novolin)FDA Link 01/2014 - 03/2005
2	Glucose (Dextrose)FDA LinkGeneric 01/2014 - 01/2014
2	Carrier Proteins (Binding Protein)IBA 01/2014 - 01/2014
2	ErbB Receptors (EGF Receptor)IBA 05/2013 - 03/2007
2	CXC ChemokinesIBA 02/2012 - 04/2006
2	Immunoglobulin G (IgG)IBA 02/2008 - 10/2002
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 12/2006 - 10/2000
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 03/2005 - 08/2003
2	Caveolin 3IBA 03/2005 - 08/2003
2	ImmunosorbentsIBA 08/2002 - 03/2002
1	Oral ContraceptivesIBA 01/2021
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 10/2018
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 10/2018
1	Aldehyde DehydrogenaseIBA 10/2018
1	isothiocyanic acidIBA 10/2018
1	Carotenoids (Carotene)IBA 10/2018
1	Mixed Function Oxygenases (Monooxygenases)IBA 10/2018
1	lecithin-retinol acyltransferaseIBA 10/2018
1	Retinoic Acid 4-Hydroxylase (CYP26B1)IBA 10/2018
1	Subfamily B ATP Binding Cassette TransporterIBA 01/2018
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2018
1	Parathyroid Hormone (Parathormone)IBA 01/2018
1	IonsIBA 01/2018
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2018
1	Calcium-Sensing ReceptorsIBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	SphingolipidsIBA 01/2018
1	sphingosine kinaseIBA 01/2018
1	CalciumIBA 01/2018
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2018
1	Lipid PeroxidesIBA 11/2016
1	PlasticsIBA 11/2016
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	LipidsIBA 01/2016
1	SphingosineIBA 01/2016
1	Streptozocin (Streptozotocin)FDA Link 01/2014
1	Free Radical ScavengersIBA 01/2014
1	Tocopherols (Tocopherol)IBA 01/2014

Therapy/Procedure

11	Therapeutics 01/2011 - 10/2002
1	Oral Administration 01/2016
1	Intraperitoneal Injections 01/2014